One of the leading causes of infertility in women today is diminished ovarian reserve (DOR).
DOR is characterized by a low number of eggs in a woman’s ovaries and/or poor quality of
the remaining eggs, which boils down to impaired development of the existing eggs, even with
assisted reproductive techniques. A good number of such women with a low ovarian reserve may
conceive with their eggs if they are given individualized treatment that is tailored for their
profile. The sooner the treatment is started, the better the chances of pregnancy.
What is ovarian reserve?
Ovarian reserve refers to the ease at which an individual’s ovaries can be successfully stimulated
with fertility drugs. The single most consistent variable affecting ovarian reserve is the woman’s
age. This is because a woman is born with all the eggs she will ever have. In most women, a
majority of the eggs are genetically normal or balanced. However, there will be some that are
genetically abnormal or unbalanced. It appears that the best eggs are ovulated first. The older a
woman is, the fewer genetically balanced eggs she has left to respond to fertility drugs. This age
relationship holds even in the fertile population. In older women, fewer normal embryos are
available for implantation into the uterus. Hence, healthy women over 35 are less fertile than
their younger counterparts. Women 40 and over may have only a 10% live birth rate with IVF
treatment using their eggs. This is why donor egg therapy has become so popular in this age
Women with a low ovarian reserve struggle to get pregnant, however, in some instances, there could
be a problem in conceiving. The menstrual cycle can vary with the heavy and light flow or be
late or shorter. Low ovarian reserve can also lead to miscarriage.
Several elements motivate low ovarian reserve, such as:
• Excess intake of alcohol
• Tubal diseases
• Radiation therapy
• Infections withinside the pelvic area
• Autoimmune disorders
• Genetic abnormalities
Common Tests to Check Ovarian reserve:
There are several tests used to identify poor ovarian reserve. Some of them are:
- (FSH) and the clomiphene citrate challenge test (CCCT)
- Measures of inhibin, Mullerian inhibiting factor, and a variety of provocative response tests
have been used less frequently
- More recently, ultrasound has also been used to anticipate stimulation response
- The basal FSH test is a blood test drawn on the second or third day of the menstrual cycle.
- The CCCT test was developed as a refinement to the basal FSH test for women 35 years of
age or older.
Young women with few oocytes may still have one or two eggs capable of resulting in a live
birth. Ovarian reserve testing identifies patients that have a lower probability of conceiving.
There are possibilities to conceive despite low ovarian reserve, however, early analysis and
proper treatment should assist to enhance the possibilities better. We can evaluate the ovarian
reserve by endorsing it by doctors to realize the function and quality of the ovary.
As the circumstances differ with the difference in ovarian evaluation, the physician can suggest
IVF or any other treatment related to infertility.
Curious about your level of ovarian reserve and your options? At Aaradhya, the doctors are
certified in carrying out ovarian reserve evaluations for couples suffering from infertility and
those who are planning for a baby. Call us at 8886592229 or visit https://bit.ly/3nHO7Ou